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Persons who are on drugs which suppress the immune system are more susceptible to infections than healthy individuals. Chickenpox and measles, for example, can have a more serious or even fatal course in non-immune children or adults on corticosteroids. In such children or adults who have not had these diseases, particular care should be taken to avoid exposure. How the dose, route and duration of corticosteroid administration affects the risk of developing a disseminated infection is not known. The contribution of the underlying disease and/or prior corticosteroid treatment to the risk is also not known. If exposed to chickenpox, prophylaxis with varicella zoster immune globulin may be indicated.
Withdrawal is more likely if you have used prednisolone for a long time or in high doses. Average and large doses of hydrocortisone or cortisone can cause elevation of blood pressure, salt and water retention, and increased excretion of potassium. Notwithstanding the numerous different advantages, it very well may be utilized in the treatment of serious unfavorably susceptible responses.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. If you notice other effects not listed above, contact your doctor or pharmacist. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. It also contains alcohol 5%, citric acid, edetate disodium, glycerin, propylene glycol, purified water, sodium saccharin, sucrose, artificial wild cherry flavor, FD&C blue #1 and red #40.
Plasma half-life is about 3 hours in adults and somewhat less in children. Its initial absorption, but not its overall bioavailability, is affected by food. Prelonee has a biological half-life lasting several hours, making it suitable for alternate-day administration regimens. Use of ocular steroids may prolong the course and may exacerbate the severity of many viral infections of the eye .
In children or adults who have not had these diseases, particular care should be taken to avoid exposure. If a patient is exposed to chickenpox, prophylaxis with varicella zoster immune globulin may be indicated. If patient is exposed to measles, prophylaxis with pooled intramuscular immunoglobulin may be indicated. If chickenpox develops, treatment with antiviral agents may be considered. Corticosteroids may increase the risks related to infections with any pathogen, including viral, bacterial, fungal, protozoan, or helminthic infections. The appropriate dose depends on the severity of the condition and the individual response of the patient.
Do not use a household spoon because you may not get the correct dose. You are encouraged to report negative side effects of prescription drugs to the FDA. In addition to the above indications PRELONE (prednisolone ) Syrup is indicated for systemic dermatomyositis . Prednisolone Syrup, USP contains prednisolone which is a glucocorticoid.
Contact your doctor if you notice white patches in your mouth or a change in vaginal discharge. While on corticosteroid therapy, patients should not be vaccinated against smallpox. Other immunization procedures should not be undertaken in patients who are on corticosteroids, especially on high dose, because of possible hazards of neurological complications and a lack of antibody response. The severity, prognosis, expected duration of the disease, and the reaction of the patient to medication are primary factors in determining dosage.
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