Prednisolone 10mg Tablets Summary of Product Characteristics SmPC emc

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1) Acute myopathy has been reported with concomitant use of high doses of corticosteroids and anticholinergics such as neuromuscular blockers (see section 4.4). Serum potassium should be closely monitored in patients receiving glucocorticoids and potassium reducing agents. High doses of corticosteroids can cause acute pancreatitis.

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Corticosteroids should therefore be introduced to these patients only after careful consideration, and risk-modifying measures as well as extra cardiac monitoring should be considered as needed. Low dose and treatment every other day can reduce the complications of corticosteroid treatment. Prednisolone Soluble Tablets may be given early in the treatment of acute asthma attacks in children. For children over 5 years use a dose of 30-40mg prednisolone. For children aged 2-5 years use a dose of 20mg prednisolone. Those already receiving maintenance steroid tablets should receive 2mg/kg prednisolone up to a maximum dose of 60mg.

My personal sincere regret for not expressing gratitude to earlier. In animal experiments, corticosteroids have been shown to give rise to various types of malformations . After long-term treatment, reduced placental and birth weight have been observed in animals.

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Prednisolone Soluble Tablets contain the equivalent of 5mg of prednisolone in the form of the 21-disodium phosphate ester. Prednisolone sodium phosphate is a synthetic glucocorticoid with the same general properties as prednisolone itself and other compounds classified as corticosteroids. Prednisolone is four times as active as hydrocortisone on a weight for weight basis. Other effects that may occur during withdrawal or change of corticosteroid therapy include benign intracranial hypertension with headache and vomiting and papilloedema caused by cerebral oedema. Reactions are common and may occur in both adults and children. In adults, the frequency of severe reactions has been estimated to be 5-6%.